Folate is one of the most vital nutrients for human health — and also one of the most misunderstood. Many people can't properly convert folic acid into its active form, which means they’re missing out on its most important benefits.
That’s where 5-MTHF (L-methylfolate) steps in. It’s the bioactive form of folate — ready for immediate use by your body. And with Probase Nutrition’s high-potency 5-MTHF supplement, you're getting pharmaceutical-grade support for mood, brain function, cardiovascular health, and detoxification.
💡 What Is 5-MTHF?
5-MTHF (5-methyltetrahydrofolate) is the active methylated form of folate, used directly in the methylation cycle. It’s essential for:
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Neurotransmitter production (like serotonin, dopamine, norepinephrine)
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Healthy homocysteine metabolism
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DNA repair and cellular detoxification
It’s especially important for those with MTHFR gene mutations, who cannot efficiently process synthetic folic acid.
🌱 5 Key Benefits of Probase Nutrition 5-MTHF
1. Supports Mood and Mental Clarity
Helps synthesize serotonin and dopamine — critical for mood balance, focus, and emotional resilience.
2. Improves Methylation
Supports the methylation cycle — key for detox, hormone regulation, and neurological health.
3. Protects the Heart
By helping convert homocysteine into methionine, it reduces cardiovascular risk factors linked to poor methylation.
4. Essential for Preconception and Pregnancy
5-MTHF supports fetal neural development and is the preferred folate form for prenatal health — without the risks of unmetabolized folic acid.
5. MTHFR-Safe
Ideal for individuals with MTHFR polymorphisms, who may not tolerate folic acid or folinic acid well.
🌿 Why Choose Probase Nutrition?
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🔬 1,000 mcg of pure L-5-MTHF per capsule (Quatrefolic®-equivalent grade)
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🌱 Non-GMO, Gluten-Free, Soy-Free
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🚫 No synthetic folic acid or fillers
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🧬 Methylation-safe for MTHFR gene variants
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🇺🇸 Made in a cGMP U.S. facility, 3rd party tested
We don’t compromise on bioavailability — and neither should you.
💊 How to Take It
Take 1 capsule daily, preferably in the morning with food. For methylation support, stack with B12 (methylcobalamin) and TMG.
🧠 Final Thoughts
If you’ve ever struggled with mood, brain fog, or energy — and especially if you have MTHFR issues — 5-MTHF is your shortcut to clarity and balance.
Probase Nutrition 5-MTHF delivers activated folate in a form your body can use immediately. No guesswork. No conversion issues. Just powerful support for your mind, metabolism, and longevity.