Probase Urolithin A - [60-Day Supply] - with Added NR and Resveratrol, Premium Quality Cellular Health Support - Alternative to NMN, NAD, CoQ10, PQQ for Healthy Aging

Helps combat aging, improves heart health and promotes muscle strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that may improve health and longevity by serving as a precursor to NAD+. Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies.  Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders.  Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight.  Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction.  Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. 

Trans-Resveratrol provides a powerhouse of antioxidant & anti-inflammatory benefits in this crystalline powder form.  Trans-Resveratrol has shown great promise in clinical studies and is part of a group of compounds called polyphenols, which act as antioxidants to protect the body against age-related conditions. Our high potency Probase Nutrition Trans-Resveratrol provides concentrated levels of Trans-Resveratrol (99% pure) from the root of the Japanese Knotweed (Polygonum Cuspidatum).  Trans-Resveratrol is a unique antioxidant with the ability to cross the blood-brain barrier.1 Benefits May Include Support for cellular energy and mitochondrial function Activation of sirtuins Immune system support Trans-Resveratrol A variety of plants produce resveratrol as a protective response when dealing with a lack of nutrients, drought, UV radiation or to fend off bacteria, fungi, and microbes. It’s prevalent in red and purple grapes, blueberries, raspberries, mulberries, peanuts, and pistachios. About Antioxidants & Polyphenols Antioxidants are molecules that work to fight free radicals, which are compounds that are harmful to the body when there are excessive amounts. Polyphenols play a vital role in longevity and cellular health and survival by protecting the body’s tissues against oxidative stress, inflammation, and age-related illnesses. (Source) Suggested Use Take one level scoop twice daily with or without food.  *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Helps combat aging, improves heart health and promotes muscle strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+. View Certificate of Analysis » Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies.  Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders.  Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight.  Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction.  Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. 

Why Should I Take Nicotinamide Riboside? If you are looking to promote cellular energy and rejuvenate yourself, then increasing NAD+ levels should be at the top of your priority list! There are various ways in which we can increase NAD+ levels, one of the most common ways being supplementing with an NAD+ precursor. Nicotinamide riboside is one of these NAD+ precursors and thus, supplementing with nicotinamide riboside is a great way to enhance vitality!* NAD+ levels tend to decline as we age, and this can underlie some of the age-related declines in energy levels and overall vitality we oftentimes experience. With this in mind, if you are looking to regain your youthful energy, then nicotinamide riboside is the perfect fit for you! If you are trying to decide between our NR and NMN, then we need to look at where each one excels. NMN seems to take the lead when we consider purely its NAD+ elevating effects, however, NR does something quite unique! NR itself appears to be quite neuroprotective, independent from its ability to increase NAD+ levels.* So, if you are looking for the most neuroprotective NAD+ precursor, then NR is the one for you!* What is Nicotinamide Riboside? Nicotinamide riboside (NR) is a naturally occurring Vitamin B3 (niacin) derivative whose main purpose is often to be converted into either nicotinamide adenine dinucleotide (NAD+), nicotinamide (NAM) or even NMN! NR is mostly absorbed in the liver where it then begins its journey to being converted into either NAD+, NAM or NMN. There are many different foods and drinks that naturally contain NR, but at nowhere near the levels we can achieve with supplementation! Nicotinamide Riboside Benefits & Uses Promotes NAD+ levels* Promote cellular energy* Promotes brain health* NR for NAD+ Creation Nicotinamide riboside is very well researched for its function as an NAD+ precursor and is seen as one of the best ways in which to increase NAD+ levels! NAD+ plays a major role in energy production, balancing oxidation levels, metabolic function and more! Although NR isn’t the only precursor option for NAD+, it is often thought to be one of the more stable options for long-term NAD+ production and for brain specific effects.* In addition to NAD+, NR also functions as a precursor to NMN and nicotinamide (NAM). NAM helps to promote cardiovascular function while NMN promotes balanced oxidation levels and cellular function, while also acting as another highly efficient NAD+ precursor. In fact, for NR to produce NAD+, it first has to be converted to NMN! With this in mind it is then quite clear that the reason these compounds are created from NR, is due to the fact that NMN and NAM both participate in the same cycle through which NR produces NAD+. NR For Neuroprotection One of NR’s claims to fame is its neuroprotective effects. This is also where NR seems to be more specialized when compared to NMN, another highly effective NAD+ precursor. This likely has to do with the fact that NR supplementation can directly affect NR related pathways in axons of neurons, where it can then locally produce fairly high levels of NAD+. Having higher levels of NAD+ in axons appears to be a fantastic neuroprotective strategy. Things get a little bit more interesting when we really dive into the research behind NR’s neuroprotective effects though. It appears that NR itself is producing some of these neuroprotective effects, as NR seems to be more neuroprotective when compared to NAD+ itself. This further points to the fact that NR is the best NAD+ precursor to take if neuroprotection is one of your main goals!  *Attention: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.